Ginkgo Biloba: What the Evidence Actually Shows
Ginkgo is one of the best-tested memory supplements, and the results are mostly negative. Prevention, healthy memory, dementia and safety.

Ginkgo is one of the best-tested memory supplements, and the results are mostly negative. Prevention, healthy memory, dementia and safety.

“Biohacking” gets treated as one philosophy, but sauna, cold exposure, HRV tracking, and fasting each have wildly different evidence behind them. Here’s what each one actually shows — including an honest null result for HRV and cognition that rarely gets mentioned.

Cognitive decline is not inevitable. 70% of cognitive ageing is modifiable — not genetic. Four mechanisms drive decline: amyloid accumulation (addressed by N3 sleep for glymphatic clearance), neuroinflammation (Mediterranean diet and DHA), vascular damage (aerobic exercise and blood pressure control), and synaptic reserve depletion (language learning, musical training, cognitive challenge). Prevention must begin in midlife — amyloid accumulation starts 15-20 years before symptoms. The evidence is specific enough to match interventions to mechanisms.