L-tyrosine is marketed as a daily focus pill, but the evidence tells a narrower story: it’s a catecholamine precursor that protects cognition specifically under stress — cold, sleep loss, heavy load — and does little otherwise. Here’s what the trials actually support, where it can backfire, and how to use it situationally rather than every day.
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Working memory is the cognitive function most directly responsible for how intelligent you seem — and how intelligent you feel. Understanding its biological capacity limit (4 ± 1 chunks), why the prefrontal cortex is uniquely vulnerable to stress and sleep deprivation, and the specific interventions with RCT evidence for improvement is the difference between vague advice and a precision protocol. This guide covers the neuroscience, the clinical evidence, and the four-layer optimisation protocol that Peter has refined across 40+ Creyos testing sessions.
Creatine is the most thoroughly researched supplement in human history and the most overlooked compound in cognitive enhancement. Working memory improvements confirmed in multiple RCTs. Sleep deprivation cognitive protection confirmed with brain imaging (2024). 30+ years of safety data with no serious adverse effects. Cost: approximately 20–40p per day. This complete guide covers the mechanism, the benchmark trials, why vegetarians show the largest effects, and the Creapure® quality standard that matters.
Alpha-GPC is a pharmaceutical compound approved by prescription in Europe that most people treat like a casual supplement. After 18+ years of research and the 2,044-patient clinical trial that no other cholinergic supplement can match, this complete guide covers what Alpha-GPC actually does, what the evidence shows, the TMAO cardiovascular consideration every user needs to understand, the 50% vs 99% form stability distinction, and the Bacopa Monnieri pairing that makes it most powerful.
